Those who sell the panic sell the cure.
While rates plummeted from the late 1980s to 2010s, polio incidence is rising again.
The failure of polio inoculations.
“The reason has to do with the type of vaccine used in many parts of the world, primarily in low- and middle-income countries. While the United States and other Western countries inject an inactivated virus that poses no risk of spread and are now polio-free, other countries rely on an oral vaccine. It’s cheap, it’s easy to administer and two or more doses confer lifelong immunity. But it’s made with living, weakened virus. And that poses a problem,” NPR explains.
“And now countries that had previously eradicated polio in Africa, the Middle East and parts of Asia are seeing new outbreaks of vaccine-derived polio,” continued the report.
"And now countries that had previously eradicated polio in Africa, the Middle East and parts of Asia are seeing new outbreaks of vaccine-derived polio."https://t.co/7t23R0sYbP
— The HighWire (@HighWireTalk) May 3, 2022
What’s the solution to treat vaccine-derived polio?
Another oral polio vaccine.
When you try repeating something expecting different results, that’s the definition of insanity.
But that’s the business model for the Bill & Melinda Gates Foundation.
Now here is a business model every industry could profit from – Create a problem and then develop the product to fix it. These guys are good. https://t.co/S7ygHj0ws4
— Del Bigtree (@delbigtree) May 4, 2022
As NPR points out, most cases of polio today are from the vaccine. Instead of halting Gates’s immensely profitable & dangerous oral polio vaccine initiative, they’re developing another vaccine to stop the spread of vaccine derived polio (funded by Gates!)https://t.co/RiYkiIQ2ue
— Jeremy Loffredo (@loffredojeremy) May 1, 2022
Over the past few years, Andino and his collaborators have been developing a new oral vaccine due to the recent outbreaks of vaccine-derived polio and an influx of funding from the Bill & Melinda Gates Foundation. The novel vaccine still contains a weakened version of the virus, but it’s been hobbled even further.
“What we did is three independent modifications” to make reactivation less likely, says Andino. The researchers tweaked the virus so that it has to accumulate more mutations to become virulent and has a harder time amassing those mutations. For example, they’ve altered the polymerase, one of the key enzymes responsible for introducing mutations, reducing its ability to mix and match genes from different viruses.
After performing well in clinical trials, the vaccine was approved for emergency use by the World Health Organization last year. Since March 2021, 265 million doses have been administered to children across 14 countries, primarily in Africa, which have either seen documented cases of vaccine-derived polio or are neighbors to locations where this type of polio has been recorded.
Dr. Modjirom Ndoutabe, the polio coordinator in WHO’s Regional Office for Africa, hopes this new vaccine will help turn a corner when it comes to eradication. “I am confident we can very quickly [stop] this outbreak,” he says.
In fact, following an assessment by a team from the Global Polio Eradication Initiative, an official declaration was made that Tajikistan’s polio outbreak was the first to be stopped following supplemental use of the new vaccine.
But some polio researchers are skeptical — like Svea Closser, a medical anthropologist at the Johns Hopkins Bloomberg School of Public Health who studies vaccination programs with a focus on polio. She says public health officials have made similar declarations that polio was on the cusp of eradication before — only to be stymied by viral mutation and logistical complications with distributing vaccines.
“On the other hand,” she adds, “if you have an oral polio vaccine that truly doesn’t cause vaccine-derived polio, it’s something that we’ll probably need in order to secure eradication eventually.”
How about shutting down these programs and stripping massive profits earned from experimenting on humans?
Unfortunately, they’ve started rolling out the new vaccine to several countries.
Uganda is one of the countries used for the experiment.
“Over just two weeks this January, Uganda vaccinated more than 8 million children with no side effects reported,” says Dr. Sabrina Kitaka, an infectious disease pediatrician at Makerere University in Kampala.
While Uganda has yet to report vaccine-derived polio cases this year, how long until there’s a breakout?
If an outbreak occurs, expect the Bill & Melinda Gates Foundation to fund the development of another vaccine.